Rule of 10 : Pheochromocytoma

As previous site was dedicated to certain medical conditions that can be described with a certain number. So is this blog. This collects Number 5-10.

Rule of 10

Pheochromocytoma 

Pheochromocytoma is a tumor most commonly arising from the adrenal medulla and secrete catecholamines (Adrenaline and Noradrenaline) in the vascular system however 10% arise from extraadrenal sites such as sympathetic chain around spinal cord, aorta, ureter and bladder. Generally these are benign tumors but 10% are malignant. 90 % occurs unilaterally and 10% occur in the family. Recently 10 gene mutations have been associated with the condition to add up to its list of 10. It rarely occurs in children (10%). And has tendency to recur (10%) even after surgical excision. 10% have been identified after the patient develops Stroke following malignant Hypertension.

Rule of 10 in pheochromocytoma

Rule of Two: Meckel's Diverticulum

Meckel’s Diverticulum

It is a blind ended tube arising from the ante-mesenteric border of the intestine and is a remnant of Vitellointestinal Duct. It also follows the rule of two i.e it is 2 inch in length, 2 feet proximal to ileocaecal junction, occurring in only 2 % of population, 2% being symptomatic and 2 types of ectopic tissues found i.e Gastric and Pancreatic. 2 times more common in male and onset is around 2 years of age.

Rule of two in Meckel's Diverticulitis