Difference between Marasmus and Kwashiorkor 
| Difference between Marasmus and Kwashiorkor | 
| 
Marasmus | 
Kwashiorkor | |
| 
Welcome Trust definition  | 
<60% without edema | 
60-80% with edema | 
| 
Stunting + Wasting below 3rd Centile  | ||
| 
Physiological State | 
Catabolism  | 
Very low anabolism  | 
| 
Theory  | ||
| 
Classical | 
Low energy → Fat and Muscle wasting  | 
Low protein → low oncotic pressure → edema | 
| 
Gopalan’s ( Theory of dysadaptabilty ) | 
Chronic Adaptation to starvation | 
Inability to adapt to nutritional stress → edema and epithelial damage | 
| 
Golden’s Theory (Free Radical Imbalance) | 
Imbalance between production and disposal of free radical  | 
Inability to produce protein  | 
| 
Signs and Symptoms | ||
| 
Appearance | 
Old man/ Monkey facies 
Baggy pant appearance  | 
Moon face appearance 
Puffy Sugar baby Appearance  | 
| 
Age  | 
Infants | 
1-5 years | 
| 
Prevalance | 
More common  | 
Less common | 
| 
Limbs | 
Wasted  
Subcutaneous tissue emaciated | 
Wasted but masked by edema 
Weak hypotonic limbs | 
| 
Skin and hair | 
Hypopigmented hair and dry scaly skin  | 
Flaky paint skin   
Flag sign (Alteranting hypo and hyper pigmentation of hair) | 
| 
Abdomen | 
Distended but not ascetic  | 
Hepatomegaly (fatty liver) | 
| 
Petechial rashes (liver damage, low clotting factor) | ||
| 
Infection  | 
Low | 
High | 
| 
Mental status | 
Alert  | 
Apathetic and irritable | 
| 
Appetite  | 
Good | 
Poor | 
| 
Others | ||
| 
Serum albumin globulin ratio | 
Low | 
Very Low | 
| 
Response to treatment  | 
Good  | 
Poor | 
thanks for information
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