Difference between Marasmus and Kwashiorkor
Difference between Marasmus and Kwashiorkor |
Marasmus
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Kwashiorkor
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Welcome Trust definition
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<60% without edema
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60-80% with edema
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Stunting + Wasting below 3rd Centile
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Physiological State
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Catabolism
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Very low anabolism
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Theory
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Classical
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Low energy → Fat and Muscle wasting
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Low protein → low oncotic pressure → edema
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Gopalan’s ( Theory of dysadaptabilty )
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Chronic Adaptation to starvation
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Inability to adapt to nutritional stress → edema and epithelial damage
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Golden’s Theory (Free Radical Imbalance)
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Imbalance between production and disposal of free radical
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Inability to produce protein
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Signs and Symptoms
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Appearance
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Old man/ Monkey facies
Baggy pant appearance
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Moon face appearance
Puffy Sugar baby Appearance
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Age
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Infants
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1-5 years
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Prevalance
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More common
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Less common
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Limbs
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Wasted
Subcutaneous tissue emaciated
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Wasted but masked by edema
Weak hypotonic limbs
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Skin and hair
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Hypopigmented hair and dry scaly skin
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Flaky paint skin
Flag sign (Alteranting hypo and hyper pigmentation of hair)
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Abdomen
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Distended but not ascetic
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Hepatomegaly (fatty liver)
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Petechial rashes (liver damage, low clotting factor)
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Infection
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Low
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High
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Mental status
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Alert
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Apathetic and irritable
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Appetite
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Good
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Poor
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Others
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Serum albumin globulin ratio
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Low
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Very Low
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Response to treatment
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Good
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Poor
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thanks for information
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