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Monday, October 16, 2017

Drug of Choice of Tropical and Infectious diseases


Pathology
Drug of Choice
2nd Line therapy
Remarks
Amoebic liver abscess
Metronidazole

Along with Luminal agent (Diloxanide furoate, parmomycin, Iodoquinol)
Anthrax
Penicillin G


Antibiotic Associated Pseudomembranous colitis
Metronidazole (IV)
Oral Rifampicin

Brucellosis
Doxycycline + aminoglycosiede fro 28 days

Continuation with Doxycycline + Rofampicin for next 4-6 weeks
Chlamydia
Tetracycline
Doxycycline

Cholera
Tetracycline
Doxycycline

Cryptococcal Meninigitis
Amphotericin B
± Flucytosine
With AIDS add Fluconazole
Falciparum malaria
Quinine


Guninea Worm infestation
Niridazole
Metronidazole

Herpes Simplex
Idoxuridine


Herpes Simplex Encephalitis
Acyclovir


Kalazar
Sodium Antimony Stibogluconate/ Pentavalent Antimony


Klebsiella Pneumonia
Gentamicin + 3rd Gen Cephalosporin


Legionella
Erythromycin


Meningococcal Meninigitis
Penicillin G


Prophylaxis: Rifampicin
Mucormycosis (Craniofacial)
Amphotericin B

Along with debridement
Multidrug resistant Typhoid
Ciprofloxacin


Neurocysticercosis
Albendazole
Praziquantel

Pneumoncystis Carini/jirovecii
Cotrimoxazole


Pneumonic Plague
Tetracycline

(Chemoprophylaxis)
Schistosoma Hematobium
Praziquantel
Oxamniquine

Taenia Solium/ Taenia Saginata
Praziquantel


Toxoplamosis /Ocular toxoplasmosis
Pyrimethamine

With Sulphadiazine/ Clindamyicn
Tropical Esosinophilia Syndrome
Diethyl Carbamazepine


Varicella zoster
Ayclovir


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