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Showing posts with label TB. Show all posts
Showing posts with label TB. Show all posts

Tuesday, October 31, 2017

Important Days of Commemoration of Public Health Interest (UN WHO endorsed and not endorsed)

Days of Public Health Interest Endorsed, Adopted and Observed by United Nations and its Agencies

Date
DAY
4th February
World Cancer Day
8th March
International Women’s Day
21st march
World Down Syndrome Day
24th March
World TB Day
2nd April
World Autism Awareness Day
7th April
World Health Day
25th April
World Malaria Day
28th April
World Day For Safety At Work
23rd May
International Day To End Obstetric Fistula
31st may
World No Tobacco Day
5th June
World Environment Day
13th June
International Albinism Awareness Day
14th June
World Blood Donor Day
21st June
World Yoga Day
11th July
World Population Day
28th July
World Hepatitis Day
28th September
World Rabies Day
10th October
World Mental Health Day
13th October
International Day For Disaster Reduction
16th October
World Food Day
14th November
World Diabetes Day
19th November
World Toilet Day
19th November (3rd Sunday of November)
World Day Of Rememberance Of Road Traffic Victims
1st December
World AIDS Day
3rd December
International Day Of Persons With Disabilities



Last week of April  
World Immunization Week
1-7 August
World Breastfeeding Week
13-19 November 
World Antibiotic Awareness Week

Http://Www.Un.Org/En/Sections/Observances/International-Weeks/Index.Html
http://www.who.int/mediacentre/events/official_days/en/

4TH FEBRUARY  World Cancer Day 8TH MARCH  International Women’s Day  21ST MARCH World Down Syndrome Day  24TH MARCH  World TB Day  2ND APRIL  World Autism Awareness Day  7TH APRIL World Health Day  25TH APRIL  World Malaria Day  28TH APRIL  World Day For Safety At Work  23RD MAY  International Day To End Obstetrics Fistula  31ST MAY  World No Tobacco Day  5TH JUNE  World Environment Day  13TH JUNE  International Albinism Awareness Day  14TH JUNE  World Blood Donor Day  21ST JUNE  World Yoga Day  11TH JULY  World Population Day  28TH JULY  World Hepatitis Day  28TH SEPTEMBER  World Rabies Day  10TH OCTOBER  World Mental Health Day  13TH OCTOBER  International Day For Disaster Reduction  16TH OCTOBER  World Food Day  14TH NOVEMBER  World Diabetes Day  19TH NOVEMBER  World Toilet Day  19TH NOVEMBER (3RD SUNDAY OF NOVEMBER) World Day Of Rememberance Of Road Traffic Victims 1ST DECEMBER World AIDS Day  3RD DECEMBER International Day Of Persons With Disabilities
UN endorsed Days 

Other Days of Public Health Interest not endorsed by UN

Date
Day
February 11
World Day of Sick
February 15
World Cholangiocarnioma Day
March 12
World Glaucoma Day
March 20
World Oral Health Day
April 17
World Hemophilia day
May 8
World Redcross Day
May 12
International Nurses day
May 18
World AIDS vaccine day
1st Tuesday in March
World Asthma Day
June 26
World Vitiligo Day
September 28
International Safe Abortion Day
September 29
World Heart day
October 2
World Cerebral Palsy day
October 10
World Mental health Day
October 11
World Obesity Day
October 13
World Thrombosis Day
October 15
Global Hand Washing day
October 18
World Vasectomy day
October 20
World Osteoporosis Day
October 29
World Stroke day
2nd Thursday in October
World Sight Day
November 8
International Day of Radiology
November 12
World Pneumonia day
November 15
World COPD awareness Day
November 17
World Prematurity day
November 26
Anti Obesity Day
https://en.wikipedia.org/wiki/List_of_international_observances

FEBRUARY 11 World Day of Sick  FEBRUARY 15  World Cholangiocarnioma Day  MARCH 12  World Glaucoma Day  MARCH 20 World Oral Health Day  APRIL 17  World Hemophilia day  MAY 8 World Redcross Day  MAY 12 International Nurses day  MAY 18  World AIDS vaccine day  1ST TUESDAY IN MARCH  World Asthma Day  JUNE 26 World Vitiligo Day  SEPTEMBER 28  International Safe Abortion Day  SEPTEMBER 29  World Heart day  OCTOBER 2 World Cerebral Palsy day  OCTOBER 10  World Mental health Day  OCTOBER 11 World Obesity Day  OCTOBER 13 World Thrombosis Day  OCTOBER 15  Global handwashing day  OCTOBER 18 World Vasectomy day  OCTOBER 20 World Osteoporosis Day  OCTOBER 29 World Stroke day  2ND THURSDAY IN OCTOBER  World Sight Day  NOVEMBER 8  International Day of Radiology  NOVEMBER 12  World Pneumonia day  NOVEMBER 15  World COPD awareness Day  NOVEMBER 17  World Prematurity day  NOVEMBER 26  Anti Obesity Day
Days Not endorsed by UN 

Saturday, August 19, 2017

2017 WHO Recommendation for treatment of TB . Things you must know !!!


2017 WHO Recommendation for treatment of TB : Things you must know !!!


1.     Drug and Dosing
a.      The 2017 guideline from WHO strongly suggest the use of RIFAMPICIN based drug regimen ( 2HRZE + 4HR) for 6 months compared to 4 months course with FLUOROQUINOLONE group of drug.

b.     Always use fixed dose combination formulation for treating drug susceptible TB   than individual drug regimen.

c.      The WHO recommends use of DAILY DOSING of drugs compared to THRICE A WEEK regimen in both intensive and continuation phase.

2.      HIV and PTB
a.      ART should be started in all patient living with HIV irrespective of CD4 counts.
b.     TB treatment should be started first followed by ART within 8 weeks (as early as possible). If CD4 cell count is less than 50, it should be started with in 2 weeks.
c.      A 6 months regimen of ATT is enough for patient under ART and 8 months course is not needed.

3.     Steroid
a.      WHO strongly recommends the initial use of steroid (Dexamethasone / Prednisolone) tapered over a period of 6-8 weeks in TB MENINGITIS. While the use of steriod of pericarditis the conditionally recommended.

4.     Retreatment
a.      Category II (2HRZES+1HRZE+5HRE) should no longer be prescribed  
without Drug sensitivity and testing.





The recommendations that still holds valid from 2010 are:
 

1.     Drug and Dosing
a.      New patient with PTB must receive 6 months of ATT therapy (2HRZE + 4HR) that is a Rifampicin based therapy and NOT that contains 2HRZE + 4HE.
b.     The use of daily dosing regimen should be practiced as far as feasible and twice daily dose should never be  used. There were recommendation for use of thrice weekly dose however the newer recommdation strongly favors use of daily dosing regimen.
c.      In areas with high resistance for Isoniazid, the expert recommend the use of HRE in continuation phase rather than HR alone.
d.     The extension of intensive phase is NOT recommended strongly even if the patient is not sputum negative at the end of Intensive phase
2.     TB and HIV
a.      WHO strongly recommends use of Rifampicin based therapy for the patients living with TB and HIV or patient living in high TB prevalent area.
b.     The duration should be NO LESS THAN those with HIV NEGATIVE status that is 6 months.There was suspicion over need of prolonged therapy but the newer recommedation suggests 6 month is sufficient.
c.      The DAILY DOSE THERAPY is recommended.

3.     Re-treatment
a.      The specimen for culture and sensitivity must be obtained in any patient going for re-treatment and sensitivity testing must be done at least for ISONIAZID and RIFAMPICIN.
b.     If possible the therapy should be guided based upon Rapid Molecular susceptibility testing.

For other details and full text follow the link to http://apps.who.int/iris/bitstream/10665/255052/1/9789241550000-eng.pdf?ua=1

Wednesday, January 13, 2016

Tuberculosis, Focuses, Complexes


1. Ghon focus(subpleural)
2. Ranke focus(ghon focus+enlarged/calcified lymphnode).
3. Puhls focus-apex
4. Assman focus- Deep apical
5. Simon focus-Subpleural focus in upper lobe
6. Aschoff-puhl focus-coarse granular dissemination.
7. Rich's focus- brain(cortex).
8. Simmond's focus-liver.
9. Wigard's focus-blood vessel(intima).

Ghon focus is a primary lesion usually subpleural, often in the mid to lower zones, caused by mycobacterium bacilli (tuberculosis) developed in the lung of a nonimmune host (usually a child). It is named for Anton Ghon (1866–1936), an Austrian pathologist.
It is a small area of granulomatous inflammation, only detectable by [chest X-ray] if it calcifies or grows substantially (seetuberculosis radiology).Typically these will heal, but in some cases, especially in immunosuppressed patients, it will progress to miliary tuberculosis (so named due to thegranulomas resembling millet seeds on a chest X-ray). 
The classical location for primary infection is surrounding the lobar fissures, either in the upper part of the lower lobe or lower part of the upper lobe.
If the Ghon focus also involves infection of adjacent lymphatics and hilar lymph nodes, it is known as the Ghon's complex or primary complex. When a Ghon's complex undergoes fibrosis and calcification it is called a Ranke complex. 
Simon focus is a tuberculosis (TB) nodule that can form in the apex of the lung when a primary TB infection elsewhere in the body spreads to the lung apex via the bloodstream. Simon focus nodules are often calcified.
The initial lesion is usually a small focus of consolidation, less than 2cm in diameter and located within 1 to 2 cm of the apical pleura.In adolescence, Simon foci may become reactivated and develop into Assmann foci. Such foci are sharply circumscribed, firm, gray-white to yellow areas that have a variable amount of central caseation and peripheral fibrosis.
Rich focus is a tuberculousgranuloma occurring on the cortex of the brain that ruptures into the subarachnoid space, causing tuberculous meningitis.It is named for Arnold Rice Rich who first described it.
Primary TB
1. Ghon focus(subpleural)
2. Ranke focus(ghon focus+enlarged/calcified lymphnode).
3.Puhls focus-apex
1. Assman focus- Deep apical
2. Simon focus-Subpleural focus in upper lobe
3. Aschoff-puhl focus-coarse granular dissemination.
4. Rich's focus- brain(cortex).
5. Simmond's focus-liver.
6. Wigard's focus-blood vessel(intima).

Secondary TB

Puhls focus: cerebellar focus
Weigerts focus: sub initimal focus

Simond focus: Liver focus
Collected from wikipedia and internet. 
Just collected. Copied and pasted.